Esterification Methods, Reactions and Applications

Novel biocatalytic esterification reactions on fatty acids:

Aspergillus terreus lipase has exhibited novel capability of catalyzing esterification reaction between fatty acids (C4-C18) and primary, secondary and tertiary monohydric alcohols. Although, the lipase efficiently catalyzed the esterification of saturated stearic acid (C18:0), it failed to accept the monounsaturated oleic acid (C18:1) as the substrate which is also a C18 acid, but has a double...

Esterification reactions of lipase in reverse micelles.

The activities of lipase from Candida cylindracea and Rhizopus delemar have been investigated in water/AOT/iso-octane reverse micellar media through the use of two esterification reactions: fatty acid-alcohol esterification and glyceride synthesis. Such media promotes the occurrence of these two lipase-catalyzed reactions due to its low water content. The effect of various parameters on the act...

Sequential Methods and Their Applications

Accelerated Growth of Dendrimers via Thiol-Ene and Esterification Reactions

By taking advantage of the orthogonal nature of thiol-ene coupling and anhydride based esterification reactions, a facile and chemoselective strategy to dendritic macromolecules has been developed. The ability to interchange growth steps based on thiol-ene and anhydride chemistry allows the synthesis of fifth-generation dendrimers in only five steps and under benign reaction conditions. In addi...

Genetically modified mice- Methods, applications and outlook

Background & Aim: Transgenic mice, of tengenerated by random integration of foreign genes into the mouse genome or by targeted mutation in a particular gene, have demonstrated to be a very effective tool for studying gene function in living things. In this review article, we discussed on the current methods of generating genetically-modified mice and their related problems and then investigated...